Five cases of serious skin reactions, including Stevens-Johnson syndrome (SJS), acute generalised exanthematous pustulosis (AGEP) and erythema multiforme have been reported in patients taking galantamine.
Discontinue if rash occurs
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Patients being treated with galantamine should be advised to discontinue treatment and seek medical help immediately if any of the following symptoms occur:
- severe rash with blisters and peeling skin, particularly around the mouth, nose, eyes and genitals (SJS).
- red rash covered with small pus-filled bumps that can spread over the body, sometimes with a fever (AGEP).
- rash that may blister, with spots that look like small targets (erythema multiforme).